Chapter 16: Certain conditions originating in the perinatal period (P00–P96)
Conditions that begin in the newborn period: prematurity and low birth weight, newborn jaundice, breathing problems of the newborn, feeding difficulties and infections acquired around birth.
Chapter 16 spans codes P00–P96 in the FY2027 ICD-10-CM tabular list. This guide explains 10 of its most common codes — select a code for its official description, a plain-English explanation and a note on when the code is used.

Codes in this chapter
| Code | Official description | In plain words |
|---|---|---|
| P07.30 | Preterm newborn, unspecified weeks of gestation | A preterm newborn is a baby born before 37 completed weeks of pregnancy; the exact gestation is not specified here. |
| P22.0 | Respiratory distress syndrome of newborn | Respiratory distress syndrome of the newborn is breathing difficulty from immature lungs lacking surfactant, mainly in preterm babies. |
| P22.9 | Respiratory distress of newborn, unspecified | Respiratory distress of a newborn baby, recorded without the type or cause being specified. |
| P36.9 | Bacterial sepsis of newborn, unspecified | Bacterial sepsis of the newborn is a serious bloodstream infection in the first weeks of life; the organism is not specified. |
| P59.9 | Neonatal jaundice, unspecified | Neonatal jaundice is yellowing of a newborn's skin from bilirubin build-up as the liver matures; cause not specified. |
| P61.2 | Anemia of prematurity | Anaemia of prematurity is the low haemoglobin seen in preterm babies as their blood production adjusts after birth. |
| P70.1 | Syndrome of infant of a diabetic mother | Syndrome of an infant of a diabetic mother: effects in a newborn whose mother has diabetes, such as low blood sugar after birth. |
| P77.9 | Necrotizing enterocolitis in newborn, unspecified | Necrotising enterocolitis is a serious bowel condition of newborns, mainly preterm babies, in which bowel tissue becomes inflamed and damaged. |
| P84 | Other problems with newborn | Asphyxia/hypoxia recorded in a newborn: another problem with oxygen supply around the time of birth, as documented. |
| P92.9 | Feeding problem of newborn, unspecified | A feeding problem in a newborn baby, such as poor sucking or slow feeding; the type is not specified. |
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
Other chapters
- Chapter 1: Infectious & Parasitic Diseases
- Chapter 2: Neoplasms
- Chapter 3: Blood & Immune Disorders
- Chapter 4: Endocrine, Nutritional & Metabolic
- Chapter 5: Mental, Behavioral & Neurodevelopmental
- Chapter 6: Nervous System
- Chapter 7: Eye & Adnexa
- Chapter 8: Ear & Mastoid Process
- Chapter 9: Circulatory System
- Chapter 10: Respiratory System
- Chapter 11: Digestive System
- Chapter 12: Skin & Subcutaneous Tissue
- Chapter 13: Musculoskeletal & Connective Tissue
- Chapter 14: Genitourinary System
- Chapter 15: Pregnancy, Childbirth & Puerperium
- Chapter 17: Congenital & Genetic Disorders
- Chapter 18: Symptoms, Signs & Abnormal Findings
- Chapter 19: Injury & Poisoning
- Chapter 20: External Causes of Morbidity
- Chapter 21: Factors Influencing Health Status
- Chapter 22: Codes for Special Purposes