Chapter 13: Diseases of the musculoskeletal system and connective tissue (M00–M99)
Bones, joints, muscles and connective tissue: arthritis and joint disorders, back and neck pain, osteoporosis, soft-tissue problems such as tendinitis and bursitis, lupus and other connective-tissue diseases.
Chapter 13 spans codes M00–M99 in the FY2027 ICD-10-CM tabular list. This guide explains 65 of its most common codes — select a code for its official description, a plain-English explanation and a note on when the code is used.

Codes in this chapter
| Code | Official description | In plain words |
|---|---|---|
| M05.9 | Rheumatoid arthritis with rheumatoid factor, unspecified | Rheumatoid arthritis in which the rheumatoid factor blood test is positive; the sites involved are not specified. |
| M06.9 | Rheumatoid arthritis, unspecified | Rheumatoid arthritis is a chronic autoimmune condition causing painful, swollen joints and progressive joint damage. |
| M10.9 | Gout, unspecified | Gout is a form of arthritis caused by uric acid crystals in a joint, causing sudden severe pain, redness and swelling. |
| M16.11 | Unilateral primary osteoarthritis, right hip | Primary osteoarthritis of the right hip: wear-and-repair damage of the hip joint cartilage causing pain and stiffness. |
| M16.12 | Unilateral primary osteoarthritis, left hip | Primary osteoarthritis of the left hip: wear-and-repair damage of the hip joint cartilage causing pain and stiffness. |
| M17.0 | Bilateral primary osteoarthritis of knee | Primary osteoarthritis of both knees: cartilage wear in the knee joints causing pain, stiffness and reduced mobility. |
| M17.11 | Unilateral primary osteoarthritis, right knee | Primary osteoarthritis of the right knee: cartilage wear causing pain and stiffness in the knee. |
| M17.12 | Unilateral primary osteoarthritis, left knee | Primary osteoarthritis of the left knee: cartilage wear causing pain and stiffness in the knee. |
| M19.90 | Unspecified osteoarthritis, unspecified site | Osteoarthritis is joint damage from cartilage wear causing pain and stiffness; site and type unspecified here. |
| M20.10 | Hallux valgus (acquired), unspecified foot | Hallux valgus is a bunion: the big toe angles toward the other toes with a bony lump at its base; foot not specified. |
| M25.50 | Pain in unspecified joint | Pain in a joint, recorded without the joint being specified; a symptom code used while the cause is assessed. |
| M25.511 | Pain in right shoulder | Pain in the right shoulder, a symptom code used while the cause (such as rotator cuff disease) is assessed. |
| M25.512 | Pain in left shoulder | Pain in the left shoulder, a symptom code used while the cause is assessed. |
| M25.551 | Pain in right hip | Pain in the right hip, a symptom code used while the cause is assessed. |
| M25.552 | Pain in left hip | Pain in the left hip, a symptom code used while the cause is assessed. |
| M25.561 | Pain in right knee | Pain in the right knee, a symptom code used while the cause is assessed. |
| M25.562 | Pain in left knee | Pain in the left knee, a symptom code used while the cause is assessed. |
| M25.571 | Pain in right ankle and joints of right foot | Pain in the right ankle and the joints of the right foot, recorded as a symptom while the cause is assessed. |
| M25.572 | Pain in left ankle and joints of left foot | Pain in the left ankle and the joints of the left foot, recorded as a symptom while the cause is assessed. |
| M32.9 | Systemic lupus erythematosus, unspecified | Systemic lupus erythematosus (SLE) is an autoimmune condition that can affect skin, joints, kidneys, blood and other organs. |
| M34.9 | Systemic sclerosis, unspecified | Systemic sclerosis (scleroderma) is an autoimmune condition causing thickening of skin and scarring of internal organs. |
| M35.00 | Sjogren syndrome, unspecified | Sjögren syndrome (sicca syndrome) is an autoimmune condition mainly causing dry eyes and dry mouth; type unspecified here. |
| M35.3 | Polymyalgia rheumatica | Polymyalgia rheumatica is an inflammatory condition of older adults causing aching and stiffness in the shoulders and hips. |
| M41.9 | Scoliosis, unspecified | Scoliosis is a sideways curvature of the spine, most often appearing in adolescence; type not specified here. |
| M43.16 | Spondylolisthesis, lumbar region | Spondylolisthesis is slippage of one vertebra forward over the one below it, here in the lumbar (lower back) region. |
| M47.812 | Spondylosis without myelopathy or radiculopathy, cervical region | Cervical spondylosis is age-related wear of the neck (cervical) spine joints and discs, here without nerve or cord compression. |
| M47.816 | Spondylosis without myelopathy or radiculopathy, lumbar region | Lumbar spondylosis is age-related wear of the lower back joints and discs, here without nerve or cord compression. |
| M48.02 | Spinal stenosis, cervical region | Spinal stenosis in the neck: narrowing of the spinal canal in the cervical region that can press on the spinal cord. |
| M48.061 | Spinal stenosis, lumbar region without neurogenic claudication | Lumbar spinal stenosis is narrowing of the spinal canal in the lower back, here without leg pain from nerve compression when walking. |
| M48.062 | Spinal stenosis, lumbar region with neurogenic claudication | Lumbar spinal stenosis with neurogenic claudication: canal narrowing in the lower back causing leg pain and heaviness when walking. |
| M50.30 | Other cervical disc degeneration, unspecified cervical region | Cervical disc degeneration is wear and drying of the discs in the neck, a common cause of neck pain and stiffness. |
| M51.16 | Intervertebral disc disorders with radiculopathy, lumbar region | A lumbar disc disorder with radiculopathy: a lower-back disc problem that presses on a nerve root, causing leg pain (sciatica). |
| M51.26 | Other intervertebral disc displacement, lumbar region | Displacement (herniation or bulge) of a disc in the lumbar spine, which may press on nearby nerves. |
| M54.12 | Radiculopathy, cervical region | Cervical radiculopathy is pain, numbness or weakness in the arm from a pinched nerve root in the neck. |
| M54.16 | Radiculopathy, lumbar region | Lumbar radiculopathy is pain, numbness or weakness down the leg from a pinched nerve root in the lower back (sciatica-type pain). |
| M54.2 | Cervicalgia | Cervicalgia is pain in the neck, recorded as a symptom while the cause is assessed. |
| M54.31 | Sciatica, right side | Sciatica on the right side: pain radiating from the lower back down the back of the right leg, along the sciatic nerve. |
| M54.32 | Sciatica, left side | Sciatica on the left side: pain radiating from the lower back down the back of the left leg. |
| M54.41 | Lumbago with sciatica, right side | Low back pain (lumbago) radiating down the right leg in a sciatica pattern. |
| M54.42 | Lumbago with sciatica, left side | Low back pain (lumbago) radiating down the left leg in a sciatica pattern. |
| M54.50 | Low back pain, unspecified | Low back pain (lumbago) recorded without a specified cause or radiation pattern. |
| M54.9 | Dorsalgia, unspecified | Dorsalgia means pain in the back; here the region and cause are not specified. |
| M62.81 | Muscle weakness (generalized) | Generalised muscle weakness is reduced strength in muscles throughout the body, recorded as a finding while the cause is assessed. |
| M62.838 | Other muscle spasm | Muscle spasm in a site other than the neck and back: a sudden, involuntary tightening of a muscle. |
| M65.30 | Trigger finger, unspecified finger | Trigger finger is catching or locking of a finger as it bends, from a thickened tendon sheath; finger not specified. |
| M67.40 | Ganglion, unspecified site | A ganglion is a benign fluid-filled swelling arising from a joint or tendon sheath, often at the wrist; site not specified. |
| M72.0 | Palmar fascial fibromatosis [Dupuytren] | Dupuytren contracture is thickening and shortening of the tissue under the palm skin, gradually bending the fingers. |
| M75.101 | Unspecified rotator cuff tear or rupture of right shoulder, not specified as traumatic | A tear or rupture of the rotator cuff of the right shoulder not attributed to a specific injury, with completeness unspecified. |
| M75.102 | Unspecified rotator cuff tear or rupture of left shoulder, not specified as traumatic | A tear or rupture of the rotator cuff of the left shoulder not attributed to a specific injury, with completeness unspecified. |
| M75.41 | Impingement syndrome of right shoulder | Impingement syndrome of the right shoulder: the rotator cuff tendons are pinched under the shoulder blade's bony arch, causing pain on lifting. |
| M75.42 | Impingement syndrome of left shoulder | Impingement syndrome of the left shoulder: pinching of the rotator cuff tendons causing pain on lifting the arm. |
| M76.61 | Achilles tendinitis, right leg | Achilles tendinitis is inflammation or degeneration of the right Achilles tendon, causing pain at the back of the heel. |
| M76.62 | Achilles tendinitis, left leg | Achilles tendinitis is inflammation or degeneration of the left Achilles tendon, causing pain at the back of the heel. |
| M77.11 | Lateral epicondylitis, right elbow | Lateral epicondylitis ('tennis elbow') of the right elbow: pain where the forearm extensor tendons attach to the outer elbow. |
| M77.12 | Lateral epicondylitis, left elbow | Lateral epicondylitis ('tennis elbow') of the left elbow: pain at the outer elbow from the forearm tendon attachment. |
| M79.10 | Myalgia, unspecified site | Myalgia means muscle pain; the site is not specified here. |
| M79.2 | Neuralgia and neuritis, unspecified | Neuralgia and neuritis are pain and inflammation along a nerve, recorded here without a specified nerve or cause. |
| M79.641 | Pain in right hand | Pain in the right hand, recorded as a symptom while the cause is assessed. |
| M79.642 | Pain in left hand | Pain in the left hand, recorded as a symptom while the cause is assessed. |
| M79.671 | Pain in right foot | Pain in the right foot, recorded as a symptom while the cause is assessed. |
| M79.672 | Pain in left foot | Pain in the left foot, recorded as a symptom while the cause is assessed. |
| M79.7 | Fibromyalgia | Fibromyalgia is a long-term condition of widespread pain, fatigue, unrefreshing sleep and cognitive fog. |
| M81.0 | Age-related osteoporosis without current pathological fracture | Age-related osteoporosis is thinning of the bones with ageing that raises fracture risk, here without a current fracture. |
| M85.80 | Other specified disorders of bone density and structure, unspecified site | Other specified disorders of bone density and structure (such as osteopenia, low bone density below the osteoporosis range); site unspecified. |
| M86.9 | Osteomyelitis, unspecified | Osteomyelitis is infection of a bone, causing pain, fever and swelling; site and course not specified here. |
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
Other chapters
- Chapter 1: Infectious & Parasitic Diseases
- Chapter 2: Neoplasms
- Chapter 3: Blood & Immune Disorders
- Chapter 4: Endocrine, Nutritional & Metabolic
- Chapter 5: Mental, Behavioral & Neurodevelopmental
- Chapter 6: Nervous System
- Chapter 7: Eye & Adnexa
- Chapter 8: Ear & Mastoid Process
- Chapter 9: Circulatory System
- Chapter 10: Respiratory System
- Chapter 11: Digestive System
- Chapter 12: Skin & Subcutaneous Tissue
- Chapter 14: Genitourinary System
- Chapter 15: Pregnancy, Childbirth & Puerperium
- Chapter 16: Perinatal Period
- Chapter 17: Congenital & Genetic Disorders
- Chapter 18: Symptoms, Signs & Abnormal Findings
- Chapter 19: Injury & Poisoning
- Chapter 20: External Causes of Morbidity
- Chapter 21: Factors Influencing Health Status
- Chapter 22: Codes for Special Purposes